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Synthesis 2019; 51(04): 842-847
DOI: 10.1055/s-0037-1611018
DOI: 10.1055/s-0037-1611018
psp
A Facile Synthesis of N-Boc-azocan-5-one
Facultad de Química, UNAM. Grant PAIP 5000-9062.Weitere Informationen
Publikationsverlauf
Received: 15. August 2018
Accepted after revision: 16. September 2018
Publikationsdatum:
10. Oktober 2018 (online)
Abstract
The azacycloalkane 1-azocan-5-one is embedded in the structure of several products of natural origin displaying a variety of bioactivities. Two convenient and straightforward routes were developed to synthesize N-Boc-azocan-5-one from readily available raw materials featuring a ring-closing metathesis (RCM) reaction as the key step.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0037-1611018.
- Supporting Information
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