Cyclopentene Assembly by Microwave-Assisted Domino Reaction of Donor–Acceptor Cyclopropanes with Ketals

Abstract

A Lewis acid-mediated domino reaction of acetals derived from aromatic ketones with 2-(het)arylcyclopropane-1,1-diesters has been developed. The reaction provides a convenient approach to cyclopentenes and related polycyclic ring systems.

Key words

cyclopentenes - ketals - donor–acceptor cyclopropanes - ­microwave-assisted synthesis - domino reaction - Lewis acids

• References and Notes


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