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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2011; 01(01/03): 66-68
DOI: 10.1055/s-0040-1703525
Case Report

PRIMARY ANORECTAL MELANOMA- A RARE CASE REPORT WITH REVIEW OF LITERATURE

Harish S. Permi
Assistant Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
,
Michelle Mathias
Associate Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
,
Kishan Prasad
Assistant Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
,
Sunilkumar Y.
Assistant Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
,
Jayaprakash Shetty K.
Professor & HOD, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
,
J. H. Makannavar
Professor, Department of Pathology, K.S. Hegde Medical Academy, Nitte University, Deralakatte, Mangalore, Karnataka, India
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Abstract

Malignant melanoma is very rare accounting for 1% of all anorectal malignancies. Long term survival is rare, as most patients die of disseminated disease. A 64-year old female presented with the history of bleeding per rectum and constipation since 2 months with recto-sigmoidoscopy showing an exophytic growth measuring 4x3 cms obstructing the lumen of the rectum. Biopsy showed malignant spindle cell tumor, with possibilities of spindle cell variant of squamous cell carcinoma, leiomyosarcoma and malignant melanoma. The tumor cells were immunoreactive for S-100 and HMB-45, confirming malignant melanoma. MRI showed a tumor just behind the anal verge, without evidence of invasion in the sphincter or enlarged lymph nodes. An abdominal perineal resection was performed with colostomy. On four years of follow up, the patient is doing well without recurrence or metastasis. We report this case because of its rarity, diagnostic dilemmas, early diagnosis and treatment of this aggressive malignancy for better outcome and long term survival. Keywords : primary, anorectal melanoma, HMB-45.

Keywords

primary - anorectal melanoma - HMB-45


Publication History

Article published online:
20 February 2020

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