CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2022; 12(01): 83-86
DOI: 10.1055/s-0041-1734401
Case Report

Evolution of Cavitary Lesion in a Case of COVID-19 Pneumonia: A Rare Entity

Debasis Behera
1   Department of Pulmonary, Critical Care and Sleep Medicine, KIMS, Bhubaneswar, Odisha, India
,
Saswat Subhankar
1   Department of Pulmonary, Critical Care and Sleep Medicine, KIMS, Bhubaneswar, Odisha, India
,
Rajesh Venkataram
2   Department of Pulmonary Medicine, KS Hegde Medical Academy, Mangalore, Karnataka, India
,
Suman Kumar Jagaty
1   Department of Pulmonary, Critical Care and Sleep Medicine, KIMS, Bhubaneswar, Odisha, India
,
C. M. Rao
1   Department of Pulmonary, Critical Care and Sleep Medicine, KIMS, Bhubaneswar, Odisha, India
,
Ruchi Rekha Behera
3   Department of Paediatrics, SCB Medical College, Cuttack, Odisha, India
,
Pragyan Rout
1   Department of Pulmonary, Critical Care and Sleep Medicine, KIMS, Bhubaneswar, Odisha, India
› Author Affiliations

Abstract

Introduction Toward the end of 2019, a novel coronavirus was identified as the causative organism of a cluster of pneumonia cases in Wuhan, China, spreading rapidly resulting in an epidemic throughout China, followed by a global pandemic. The initial radiological findings of coronavirus disease 2019 (COVID-19) pneumonia at the early stage on a computed tomography (CT) scan include multiple small patchy shadows and interstitial inflammation, predominantly distributed in the peripheral one-third of the lungs. Gradually, it develops into multiple ground glass opacities and infiltrates in the lungs. Furthermore, pulmonary consolidation is observed, but pleural effusion is rare.

Objective From time of presentation to complete recovery, CT scans show significant morphological changes in the lesions, but very few literatures have reported cavitary lesion in the lungs. We present the case of a 64-year-old patient with COVID-19 pneumonia who had typical manifestations of the disease on a CT scan along with constantly changing small cavity in the lung.

Discussion Delayed cavitation is a rarely described radiological manifestation of COVID-19. Atypical presentations of COVID-19 raise possibility of other infections or additional diagnoses. Bacterial and fungal infection should be excluded, as well as cavity-causing organisms. Although the proper mechanism of cavitation in COVID-19 pneumonia is not known, it may be due to intra- alveolar hemorrhage, diffuse alveolar damage, and necrosis of parenchymal cells based on findings of autopsy reports. Early and late complications associated with COVID-19 are yet to be defined.

Conclusion Common causes of cavitary lesions must be investigated properly in all patients. Most cases are self-limited hence managed conservatively. The clinical spectrum of disease due to COVID-19 continues to evolve. Physicians must be aware of evolving radiological findings of COVID-19 and must conduct regular follow-up of convalescent patients with COVID-19 to ensure complete recovery.



Publication History

Article published online:
20 August 2021

© 2021. Nitte (Deemed to be University). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 World Health Organization. Novel coronavirus-China[EB/OL]. (2020–01–12) [2020–02–10]. Available at: https://www.who.int/csr/don/12-january-2020-novel-coronavirus-china/en. Accessed July 17, 2021
  • 2 Pan F, Ye T, Sun P. et al Time course of lung changes at chest CT during recovery from coronavirus disease 2019 (COVID-19. Radiology 2020; 295 (03) 715-721
  • 3 Liu K, Fang YY, Deng Y. et al Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl 2020; 133 (09) 1025-1031
  • 4 Pan Y, Guan H, Zhou S. et al Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. Eur Radiol 2020; 30 (06) 3306-3309
  • 5 Guan HX, Xiong Y, Shen NX. et al. Clinical and thin-section CT features of patients with 2019-nCoV-pneumonia. Radiol Pract 2020; . doi: DOI: 10.13609/j.cnki.1000-0313.2020.02.001.
  • 6 Shi H, Han X, Jiang N. et al Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis 2020; 20 (04) 425-434
  • 7 Xu Z, Shi L, Wang Y. et al Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med 2020; 8 (04) 420-422
  • 8 Menter T, Haslbauer JD, Nienhold R. et al Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction. Histopathology 2020; 77 (02) 198-209 DOI: 10.1111/his.14134. [Epub ahead of print: 04 May 2020]
  • 9 Yao XH, Li TY, He ZC. et al [A pathological report of three COVID-19 cases by minimal invasive autopsies]. Zhonghua Bing Li Xue Za Zhi 2020; 49 (05) 411-417