Synfacts, Table of Contents Synfacts 2023; 19(04): 0410DOI: 10.1055/s-0042-1752651 Innovative Drug Discovery and Development MK-8189: A Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia Contributor(s): Antonia F. Stepan (Roche) , Ferdinand H. Lutter (Janssen Pharmaceutica) Recommend Article Abstract Buy Article Key words Key wordsPDE10A Inhibitor - schizophrenia - cycloproanation Full Text