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Synlett 2023; 34(01): 77-80
DOI: 10.1055/s-0042-1753061
letter

Synthesis of β-Arylbutenolides Mediated by BF3·OMe2

Beatriz M. Finêncio
,
Fernanda A. Santos
,
Rosangela S. Laurentiz∗
The authors thank the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, process 2018/00544-4), the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, 313660/2020-4), and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) for scholarships and financial support.
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Abstract

The reaction of phenols or aryl ethers with tetronic acid mediated by BF3·OMe2 was investigated. This strategy allowed for the preparation of β-(hydroxyaryl)butenolides and β-arylbutenolides in a single step in a simpler way than previously reported synthetic methods

Key words

butenolides - aromatic electrophilic substitution - rubrolides - synthons - tetronic acid

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0042-1753061.
  • Supporting Information


Publication History

Received: 26 August 2022

Accepted after revision: 07 October 2022

Article published online:
03 November 2022

© 2022. Thieme. All rights reserved

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