Multivariate Linear Regression Informs Ligand Design to Improve the Synthesis of a KRAS Inhibitor

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Synfacts 2023; 19(02): 0189
DOI: 10.1055/s-0042-1753239

Innovative Drug Discovery and Development

Contributor(s):

Antonia F. Stepan (Roche)

,

Nadine Kuhl (MSD)

Negishi coupling - axial chirality - multivariate linear regression - process chemistry

Article published online:
17 January 2023

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany