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Synlett 1997; 1997(8): 1007-1009
DOI: 10.1055/s-1997-953
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Polycations: Syntheses of Polyammonium Strings as Antibacterial Agents

Jeanne Fabian, Tessie October, Alice Cherestes, Robert Engel*
  • *Department of Chemistry and Biochemistry, Queens College of the City University of New York, Flushing, NY 11367 USA, FAX: 718-997-5531; e-mail: robert_engel@qc.edu
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Publikationsdatum:
31. Dezember 2000 (online)

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A series of polyammonium species, each bearing two to ten cationic sites within the covalent structure, have been synthesized. For these species quaternary ammonium sites are located in a linear array at regular intervals along a "string" backbone with free-floating anions. The polycationic species exhibit antibacterial activity using strains of E. coli.

polycations - ammonium salts - dabco - cationic string - antibacterial