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Synlett 1999; 1999(11): 1805-1807
DOI: 10.1055/s-1999-2921
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Synthesis of Optically Active (2-Fluoroacyl)benzenes

Elke Fritz-Langhals*
  • *Consortium für Elektrochemische Industrie GmbH, Central Research Company of Wacker-Chemie GmbH, Zielstattstraße 20, D-81379 München, Germany; Fax +49-89-74 84 42 42; E-mail: Elke.Fritz-Langhals@wacker.de
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Publikationsdatum:
31. Dezember 1999 (online)

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Optically active (2-fluoroacyl)benzenes 1 which form a new class of compounds can be easily prepared from optically active 2-fluorocarboxylic acid chlorides 2 in high optical yield via Friedel-Crafts reaction using anhydrous iron trichloride as catalyst.

asymmetric synthesis - Friedel-Crafts acylation - optically active (α-fluoroacyl)benzenes