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Synlett 1999; 1999(11): 1727-1730
DOI: 10.1055/s-1999-2927
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A Practical Method for the Synthesis of β-Amino α-Hydroxy Acids. Synthesis of Enantiomerically Pure Hydroxyaspartic Acid and Isoserine

Giuliana  Cardillo* , Luca Gentilucci, Alessandra Tolomelli, Claudia Tomasini
  • *Dipartimento di Chimica "G. Ciamician", Università di Bologna and C.S.F.M., Via Selmi 2, 40126 Bologna, Italy; Tel. ++39 51 2 09 95 70; Fax ++39 51 2 09 94 56; E-mail: cardillo@ciam.unibo.it
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Publication Date:
31 December 1999 (online)

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The iodocyclization of 3-benzoylamino carboxylic acid derivatives gives oxazoline-5-carboxylates which are precursors of β-amino-α-hydroxy acids

amino acids - cyclization - iodine - chiral auxiliaries - natural products