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Synlett 2002(7): 1128-1130
DOI: 10.1055/s-2002-32598
DOI: 10.1055/s-2002-32598
LETTER
© Georg Thieme Verlag Stuttgart · New York
A Simple Protocol for the One Pot Synthesis of Chiral Secondary Benzylic Alcohols by Catalytic Enantioselective Reduction of Aromatic Ketones
Weitere Informationen
Received
13 February 2002
Publikationsdatum:
07. Februar 2007 (online)
Publikationsverlauf
Publikationsdatum:
07. Februar 2007 (online)
![](https://www.thieme-connect.de/media/synlett/200207/lookinside/thumbnails/10.1055-s-2002-32598-1.jpg)
Abstract
A simple and efficient protocol for the one-pot catalytic enantioselective reduction of prochiral aromatic ketones mediated by in situ prepared catalysts derived from (S)-(-)-diphenyl-pyrrolidin-2-yl-methanol, is reported.
Key words
enantioselective reduction - chiral alcohols - oxazaborolidines - chiral catalysts - one-pot reaction
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