The Reactivity of 4-Hydroxycoumarin under Heterogeneous High-Intensity Sonochemical Conditions [1]

Abstract

High-intensity ultrasounds have been employed in the synthesis of 4-hydroxycoumarin derivatives, using mainly water as reaction medium. Marked improvements of reaction rates, chemoselectivity and product yields have been observed on comparing sonochemical with ordinary conditions. In the alkylation of a series of allyl and benzyl bromides a pathway switch occured to yield 3-alkyl-4-hydroxycoumarin derivatives.

Key words

sonochemistry - ultrasounds - 4-hydroxycoumarin - coumarin derivatives - chemoselectivity

References

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