RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2005(0): 0029-0029
DOI: 10.1055/s-2005-865380
DOI: 10.1055/s-2005-865380
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart · New York
An Efficient Synthesis of Bibutenolides from 2,3-Allenoic Acids
S. Ma*, Z. Yu, Z. Gu
Shanghai Institute of Organic Chemistry, P. R. China
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
20. Juli 2005 (online)

Significance
A new catalytic system for the preparation of dibutenolides by a cyclization-coupling reaction of 2,3-allenoic acids is described. Three different catalytic systems involving Pd(II) and corresponding additives have been developed, in which the key step is the regeneration of the Pd(II) species to complete the catalytic cycle. The bicyclization reaction gives excellent yields and diastereoselectivity using optically active 2,3-allenoic acids.