Download PDF
Synfacts 2005(0): 0078-0078  
DOI: 10.1055/s-2005-869880
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Cooperative Catalysis by General Acid and Base Bifunctionalized Mesoporous Silica Nanospheres

Contributor(s): Yasuhiro Uozumi, Masahiro Kimura
S. Hun, H.-T. Chen, J. W. Wiench, M. Pruski, V. S.-Y. Lin*
Iowa State University, USA
Further Information

Publication History

Publication Date:
20 July 2005 (online)

   Permissions and Reprints

Significance

Bifunctinalized mesoporous silica nanospheres (MSNs) having a general acid, the ureidopropyl group (UDP), and a general base, 3-[2-(2-aminoethylamino)ethylamino]propyl group (AEP), were synthesized. The AEP/UDP-MSNs catalyzed the carbonyl activation reactions, aldol reaction, Henry reaction, and cyanosilylation with high TONs up to 22.6, 125.0, and 276.1, respectively.