Download PDF
Synfacts 2005(0): 0065-0065  
DOI: 10.1055/s-2005-869927
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

Modular Catalysts for the Enantioselective Allylation of Aldehydes

Contributor(s): Paul Knochel, Andrei Gavryushin
J.-Y. Lee, J. J. Miller, S. S. Hamilton, M. S. Sigman*
University of Utah, USA
Further Information

Publication History

Publication Date:
20 July 2005 (online)

   Permissions and Reprints

Significance

The formerly developed Mn-Cr(II)-mediated allylation of aldehydes for the first time has been performed in an enantioselective variant using a set of modular amino acid-derived ligands. Enantioselectivities of up to 95% were achieved after screening of different catalyst diastereomers.