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Synfacts 2005(0): 0054-0054  
DOI: 10.1055/s-2005-869936
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Asymmetric Allylation of Aldehydes Catalyzed by a Chiral Indium(III)-BINOL Complex

Contributor(s): Mark Lautens, Y. Eric Fang
Y.-C Teo, K.-T. Tan, T.-P. Loh*
National Univerity of Singapore, Singapore
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Publication History

Publication Date:
20 July 2005 (online)

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Significance

The first chiral indium(III)-catalyzed allylation reaction of aldehydes is disclosed. By using catalytic InCl3/(S)-BINOL, highly enantioselective formation of homoallylic alcohols was achieved using allyltributylstannane.