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Synfacts 2005(1): 0152-0152  
DOI: 10.1055/s-2005-872127
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart · New York

One-Pot Synthesis of Spiro-Cyclopropanes from Oxoallylsilanes

Contributor(s): Paul Knochel, Andrei Gavryushin
A. Barbero, P. Castreño, F. J. Pulido*
Universidad de Valladolid, Spain
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Publikationsdatum:
21. September 2005 (online)

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Significance

This method offers an easy synthetic route for polycyclic spiro-cyclopropanes from easily available starting materials. This structural motif is present in many biologically significant molecules.