Synthesis of ()-Dibromophakellstatin

K. S. Feldman; A. P. Skoumbourdis

doi:10.1055/s-2005-872160

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Synfacts 2005(1): 0105-0105
DOI: 10.1055/s-2005-872160

Synthesis of Natural Products and Potential Drugs

Synthesis of ()-Dibromophakellstatin

Contributor(s): Philip Kocienski, Thomas Snaddon
K. S. Feldman*, A. P. Skoumbourdis
Pennsylvania State University, USA

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Publication History

Publication Date:
21 September 2005 (online)

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Significance

Dibromophakellstatin is a cytotoxic pyrrole-imidazole alkaloid isolated from Phakellia mauritiana. The target molecule is cytotoxic but there is no biological impetus to its synthesis.