RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2006(1): 0020-0020
DOI: 10.1055/s-2005-921689
DOI: 10.1055/s-2005-921689
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart · New York
Synthesis of 3-Acylphospholes
M. Clochard, J. Grundy, B. Donnadieu, F. Mathey*
University of California Riverside, USA
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
16. Dezember 2005 (online)

Significance
The first method for the regioselective C3 functionalization of phospholes is presented. The reaction involves a thermal double [1,5] or [1,3] migration of an acyl group and proceeds in low to moderate yields to afford products by potassium tert-butoxide equilibrium displacement. A theoretical rationalization for the migrations is presented.