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DOI: 10.1055/s-2005-922237
© Georg Thieme Verlag Stuttgart · New York
Depressionsbehandlung heute
Current Treatment of DepressionPublication History
Publication Date:
22 November 2005 (online)
![](https://www.thieme-connect.de/media/psychoneuro/200510/lookinside/thumbnails/10.1055-s-2005-922237-1.jpg)
Zusammenfassung
Depressionen sind die häufigste psychiatrische Erkrankung. Rund 15 bis 20 % aller Menschen leiden mindestens einmal in ihrem Leben an einer depressiven Episode. Zur Therapie schneidet eine Kombination aus psychotherapeutischer und medikamentöser Behandlung besser ab als die jeweilige Monotherapie. Neue pharmakologische Optionen bieten der selektive Serotonin- und Noradrenalin-Wiederaufnahmhemmer Duloxetin sowie der enantiomerenreine selektive Serotonin-Wiederaufnahmehemmer Escitalopram. Bei bipolaren Depressionen sollte bei der Behandlung berücksichtigt werden, dass Antidepressiva einen Switch in die Manie auslösen können, weswegen gegebenenfalls eine phasenprophylaktische Therapie mit Stimmungsstabilisierern eingesetzt werden sollte.
Summary
Depressive states are the most common mental diseases. During the course of their lives some 15 to 20 % of the general population suffer from a depressive episode on at least one occasion. With regard to treatment, a combination of psychotherapeutic and pharmacotherapeutic measures proves to be superior to the respective monotherapy. New pharmacological options are available in the form of the selective serotonin and norepinephrine reuptake inhibitor, duloxetine, and the pure enantiomer selective serotonin reuptake inhibitor escitalopram. When treating bipolar depression, account must be taken of the fact that antidepressants may trigger a switch-over to the manic state, which implies that, whenever necessary, phase prophylactic therapy with mode-stabilizing drugs should be employed.
Key words
depression - treatment - diagnostic - psychotherapy
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Korrespondenzadresse:
Dr. med. univ. Dietmar Winkler
Klinische Abteilung für Allgemeine Psychiatrie, Medizinische Universität Wien
Währinger Gürtel 18-20
A-1090 Wien, Österreich
Email: dietmar.winkler@meduniwien.ac.at