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Synfacts 2007(3): 0283-0283  
DOI: 10.1055/s-2007-968272
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Ti(Oi-Pr)4-Salan Catalyzed Epoxidation of Unfunctionalized Olefins

Contributor(s): Mark Lautens, Yann Béthuel
K. Matsumoto, Y. Sawada, T. Katsuki*
Kyushu University, Fukuoka, Japan
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Publikationsdatum:
20. Februar 2007 (online)

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Significance

Over the years, numerous methods have been developed for the epoxidation of olefins (see book below). In particular, use of hydrogen peroxide as an environmentally friendly oxidant was extensively studied (B. S. Lane, K. Burgess Chem. Rev. 2003, 103, 2457-2473). In the present paper, the authors develop a Ti(Oi-Pr)4-3,3′-(ortho-substituted phenyl)salan catalyst system for epoxidation of unfunctionalized olefins using H2O2.