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Synfacts 2008(6): 0551-0551  
DOI: 10.1055/s-2008-1072599
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Cassialoin

Contributor(s): Philip Kocienski
Y. Koyama, R. Yamaguchi, K. Suzuki*
Tokyo Institute of Technology, Japan
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Publication History

Publication Date:
21 May 2008 (online)

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Significance

A significant development in the synthesis of cassialoin is the use of the a-ketol F as a selectively protected stereogenic anthrone surrogate in which the diastereotopic faces are differentiated thereby allowing control of the C-glycosidation reaction (F+G→H) at C10.