Spontaneous Corneal Perforation in Treatment-Resistant MPO-ANCA-Associated Small Vessel Vasculitis

Klin Monbl Augenheilkd 2023; 240(04): 385-386
DOI: 10.1055/a-2004-5200

Der interessante Fall

Spontane Hornhautperforation bei therapieresistenter MPO-ANCA-assoziierter Kleingefässvaskulitis

Karin Zehnder

Department of Ophthalmology, University Hospital Basel, Basel, Switzerland

,

Aja Reinhold

Department of Ophthalmology, University Hospital Basel, Basel, Switzerland

,

Konstantin Gugleta

Department of Ophthalmology, University Hospital Basel, Basel, Switzerland

,

Zisis Gatzioufas

Department of Ophthalmology, University Hospital Basel, Basel, Switzerland

References
1 Deshmukh R, Stevensen LJ, Vajpayee R. Management of corneal perforations: An update. Indian J Ophthalmol 2020; 68: 7-14
2 Fujita Y, Fukui S, Endo Y. et al. Peripheral Ulcerative Keratitis Associated with Granulomatosis with Polyangiitis Emerging Despite Cyclophosphamide, Successfully Treated with Rituximab. Intern Med 2018; 57: 1783-1788
3 Huerva V, Sanchez MC, Traveset A. et al. Rituximab for peripheral ulcerative keratitis with wegener granulomatosis. Cornea 2010; 29: 708-710
4 Fennelly E, Greenan E, Murphy CC. Corneal melt secondary to eosinophilic granulomatosis with polyangiitis. BMJ Case Rep 2019; 12: e229859
5 Messmer EM, Foster CS. Vasculitic peripheral ulcerative keratitis. Surv Ophthalmol 1999; 43: 379-396
6 Gottsch JD, Akpek EK. Topical cyclosporin stimulates neovascularization in resolving sterile rheumatoid central corneal ulcers. Trans Am Ophthalmol Soc 2000; 98: 81-90