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Synlett 2023; 34(13): 1549-1553
DOI: 10.1055/a-2033-8632
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Taming Challenging Radical-Based Convergent Paired Electrolysis with Dual-Transition-Metal Catalysis

Liubo Li 
a   Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry, Chinese Academy of Sciences, 100190 Beijing, P. R. of China
,
Niankai Fu  ∗
a   Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function Institute of Chemistry, Chinese Academy of Sciences, 100190 Beijing, P. R. of China
b   University of Chinese Academy of Sciences, 100049 Beijing, P. R. of China
› Author AffiliationsWe thank the National Natural Science Foundation of China (grant no. 22071252), the Postdoctoral Research Foundation of China (YJ20220197), and Chinese Academy of Sciences for their financial support.
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Abstract

The past few years have witnessed a renaissance of electrochemistry in organic synthesis. This green technology replaces chemical oxidants or reductants with inexpensive electricity. Paired electrolysis refers to processes in which reactions at both electrodes are desirable. These maximize the energy economy by avoiding the waste of electrical power on sacrificial reactions. Convergent paired electrolysis is a special case in which reactive intermediates are generated simultaneously at both electrodes and then coupled. However, radical-based reactions of this type remain underexploited. The incorporation of transition-metal catalysis could be beneficial by modulating the formation and utilization of highly reactive radical species. In this article, we introduce our most recent successful implementations of this strategic design.

1 Introduction

2 Ce/Ni Dual-Catalytic Decarboxylative Arylation

3 Fe/Ni Dual-Catalytic Esterification of Aryl Halides

4 Conclusion.

Key words

convergent paired electrolysis - electrochemistry - electrocatalysis - radical reaction - transition-metal catalysis


Publication History

Received: 02 February 2023

Accepted after revision: 13 February 2023

Accepted Manuscript online:
13 February 2023

Article published online:
07 March 2023

© 2023. Thieme. All rights reserved

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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