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DOI: 10.1055/a-2085-4195
ortho-Heterobimetallic Arylene Complex: A New Platform for Regioselective Difunctionalization
The financial support from the National Natural Science Foundation of China (Grant No. 22171026, 21572022 and 21372031) is gratefully acknowledged.
Abstract
Regioselective ortho difunctionalization of arenes is highly desirable yet challenging in organic synthesis. Here, we briefly discuss various methods for ortho difunctionalization of arenes and highlight a novel ortho-heterobimetallic arylene complex enabled by heterobimetallic synergism, which shows great potential in regioselective ortho difunctionalizations.
1 Introduction
2 Distinct Reactivity of C–Fe and C–Ti Bonds
3 E/E′ ODFs by Fe/Ti-Heterobimetallic Intermediate
4 Nu/E ODFs by Fe/Ti -Heterobimetallic Intermediate
5 Summary and Outlook
Publication History
Received: 09 April 2023
Accepted after revision: 03 May 2023
Accepted Manuscript online:
03 May 2023
Article published online:
26 May 2023
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