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DOI: 10.1055/a-2427-7689
Visible-Light Organophotoredox-Catalyzed Phosphonoalkylation of Alkenes via Deaminative Three-Component Radical–Radical Coupling
This work was supported by the Department of Science and Technology (DST), Ministry of Science and Technology, India, the Science and Engineering Research Board (SERB), Core Research Grant No. CRG/2021/006717. S.D. thanks CSIR, India for the fellowship.
On the occasion of 75th birthday of Prof. B. C. Ranu
Abstract
Here, we have reported a visible-light-mediated organic photoredox-catalyzed difunctionalization of vinyl arenes via radical–radical coupling. A stabilized benzylic radical at the α-position is generated via the regioselective addition of phosphonyl radical at the β-position of the styrene. Subsequently, benzyl or allyl radical, generated via the deaminative pathway from the Katritzky salt, combines with the α-radical of the styrene to furnish the functionalised C–P and C–C bonds in a single reaction.
Key words
styrene - difunctionalization - radical-polar crossover - phosphorylation - deaminative - α-alkylationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2427-7689.
- Supporting Information
Publication History
Received: 30 August 2024
Accepted after revision: 30 September 2024
Accepted Manuscript online:
30 September 2024
Article published online:
22 October 2024
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