Aldol Cyclization with a Twist: Asymmetric Approach Yields CF3-Functionalized Heterospirocycles

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Synfacts 2024; 20(12): 1325
DOI: 10.1055/a-2439-7866

Innovative Drug Discovery and Development

Aldol Cyclization with a Twist: Asymmetric Approach Yields CF₃-Functionalized Heterospirocycles

Contributor(s):

Dirk Trauner

,

Kamara Holmes

aldol condensation - spirocycles - trifluoromethylation - asymmetric synthesis

Article published online:
21 November 2024

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany