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Semin Neurol 2009; 29(2): 124-135
DOI: 10.1055/s-0029-1213733
© Thieme Medical Publishers

Peripheral Nerve Complications of Medical Disease

Hannah R. Briemberg1
  • 1Department of Medicine, Division of Neurology, Neuromuscular Disorders Unit, University of British Columbia, Vancouver, British Columbia, Canada
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Publication History

Publication Date:
15 April 2009 (online)

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ABSTRACT

Neuropathies are associated with several systemic diseases. This article provides a general overview of the clinical presentation and management of the various neuropathies associated with common medical illnesses. The term “neuropathy” is used relatively broadly to encompass pathology from the level of the cell body to the terminal axon. Peripheral nerve disorders associated with diabetes, thyroid disease, connective tissue disease, cancer, and infection are discussed. The relationship between the various neuropathies and systemic illness is important to recognize because neuropathy may be the initial presentation of one of these underlying medical conditions. Alternatively, the presence of a known associated medical condition in a patient presenting with neuropathy may affect management decisions and limit unnecessary investigations.

KEYWORDS

Peripheral neuropathy - polyneuropathy - sensory ganglionopathy - vasculitis

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Hannah R BriembergM.D. F.R.C.P.C. 

Neuromuscular Disorders Unit

2775 Laurel Street, Vancouver, BC, Canada V5Z 1M9

Email: hannah.briemberg@vch.ca