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Synfacts 2009(5): 0579-0579  
DOI: 10.1055/s-0029-1216556
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Deallylation with a Ruthenium Complex Supported on Fe3O4@SiO2

Contributor(s): Yasuhiro Uozumi, Takao Osako
T. Hirakawa, S. Tanaka, N. Usuki, H. Kanzaki, M. Kishimoto, M. Kitamura*
Nagoya University and Hitachi Maxell, Ltd., Kyoto, Japan
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Publication History

Publication Date:
22 April 2009 (online)

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Significance

Fe3O4@SiO2-L-CpRu(η³-C3H5) was prepared by immobilization of compound 1 on Fe3O4@SiO2, followed by treatment with [CpRu(MeCN)3]PF6 (eq. 1). The complex catalyzed the deallylation of allyl esters and allyl ethers to afford the corresponding alcohols in up to 99% yield (10 examples, eq. 2). The catalyst quantitatively converted Fmoc-Phe-Asp(allyl)-Ot-Bu into Fmoc-Phe-Asp-Ot-Bu without affecting the Boc and Fmoc groups (eq. 3).