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Synfacts 2011(2): 0121-0121  
DOI: 10.1055/s-0030-1259215
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Total Synthesis of (+)-Roxaticin

Contributor(s):Steven V. Ley, Catherine F. Carter
S. B. Han, A. Hassan, I. S. Ku, M. J. Krische*
University of Texas at Austin, USA
Total Synthesis of (+)-Roxaticin via C-C Bond Forming Transfer Hydrogenation: A Departure from Stoichiometric Chiral Reagents, Auxiliaries and Premetalated Nucleophiles in Polyketide Construction
J. Am. Chem. Soc.  2010,  132:  15559-15561