Download PDF
Synfacts 2011(8): 0812-0812  
DOI: 10.1055/s-0030-1260752
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of N-Methylwelwitindolinone D Isonitrile

Contributor(s): Steven V. Ley, James R. Frost
V. Bhat, K. M. Allan, V. H. Rawal*
The University of Chicago, USA
Further Information

Publication History

Publication Date:
20 July 2011 (online)

    Permissions and Reprints

Significance

Of the indole alkaloids, isolated from Fischerella muscicola and Fischerella major by Moore and co-workers, N-methylwelwitindolin­one D isonitrile is the only one differing significantly in carbon framework. This attribute, coupled with the interesting range of biological activities displayed by this class of alkaloids, has made this molecule a worthy target.