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Synfacts 2011(11): 1196-1196  
DOI: 10.1055/s-0031-1289187
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Pd-Catalyzed Enantioselective Allylic Etherizations of Oximes

Contributor(s): Hisashi Yamamoto, Jiajing Tan
Z. Cao, Z. Liu, Y. Lin, H. Du*
Institute of Chemistry, Chinese Academy of Sciences, Beijing, P. R of China
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Publication History

Publication Date:
19 October 2011 (online)

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Significance

A novel type of hybrid alkene-phosphine ligands was successfully applied to a palladium-catalyzed allylic etherization reaction with a variety of oximes as nucleophiles. The corresponding oxime ether derivatives were obtained in high yields and enantioselectivities.

Review: For an overview on chiral olefin ligands, see: R. Shintani, T. Hayashi Aldrichimica Acta 2009, 42, 31-38.