Synlett 2012(2): 275-277  
DOI: 10.1055/s-0031-1290071
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of the Antifungal Cyclic Peptides Tunicyclins C and D

Harveen Kaura,b, Amanda M. Heapya,b, Margaret A. Brimble*a,b
a School of Chemical Sciences, The University of Auckland, 23 Symonds Street, Auckland 1142, New Zealand
b Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
Fax: +64(9)3737422; e-Mail: m.brimble@auckland.ac.nz;
Further Information

Publication History

Received 3 November 2011
Publication Date:
03 January 2012 (online)

Abstract

The first synthesis of the cyclic peptides tunicyclins C and D is described. Tunicyclin D is a potent antifungal agent, isolated from a traditional Chinese medicinal herb.