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Klin Monbl Augenheilkd 2012; 229(2): 119-125
DOI: 10.1055/s-0031-1299260
Übersicht
© Georg Thieme Verlag KG Stuttgart · New York

Die Laser-Scanning-Tomographie in der Glaukomsprechstunde

Laser-Scanning-Tomography in Clinical Routine
R. O. Burk
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Publication History

21 November 2011

19 January 2012

Publication Date:
14 February 2012 (online)

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Zusammenfassung

Die Laser-Scanning-Tomografie mit dem Heidelberg Retina Tomograph HRT dient der quantitativen Analyse des Sehnervenkopfes. Die dreidimensionale Strukturrekonstruktion erfolgt aus einer tiefengeschichteten Serie zweidimensionaler optischer Schnittbilder. Die Papillentopografie wird über topometrische Parameter erfasst, anhand mathematischer Modellrechnungen wird die Abschätzung der Wahrscheinlichkeit eines Glaukomschadens ermittelt. Im klinischen Alltag hat sich aus Praktikabilitätsgründen dieses Bildgebungsverfahren als Goldstandard in der Verlaufskontrolle einer glaukomatösen Papillenschädigung etabliert.

Abstract

Scanning laser tomography using the Heidelberg Retina Tomograph (HRT) aims at a three-dimensional reconstruction of optic disk topography based on two-dimensional optical section images. Topometric parameters describe the optic disk configuration, algorithms calculate the likelihood of already existing glaucomatous tissue alterations. In the follow-up of chronic glaucoma, this imaging technique has become the gold standard for quantitative optic nerve head evaluation.

Schlüsselwörter

Scanning Laser Tomografie - Bildgebung - Glaukom - Papille

Key words

scanning laser tomography - imaging - Glaucoma - optic disk
 

  • Literatur

  • 1 EGS. Terminology and guidelines for glaucoma. 3rd. Edition Editrice DOGMA s. r.l; ISBN: 978-88-87434-28-6
  • 2 Jonas JB, Gusek GC, Naumann GOH. Optic disc morphometry in chronic primary open-angle glaucoma. Graefes Arch Clin Exp Ophthalmol 1988; 226: 531-538
    CrossrefPubMedSearch in Google Scholar
  • 3 Zinser G, Wijnaendts-van-Resandt RW et al. Confocal laser tomographic scanning of the eye. Proc SPIE 1989; 1161: 337-344
    PubMedSearch in Google Scholar
  • 4 Burk ROW. Dreidimensionale topographische Analyse des Sehnerven als Bestandteil der Glaukomdiagnose. Ophthalmologe 1992; 89: 190-203
    PubMedSearch in Google Scholar
  • 5 Kamal DS, Viswanathan AC, Garway-Heath DF et al. Detection of optic disc change with the Heidelberg retina tomograph before confirmed visual field change in ocular hypertensives converting to early glaucoma. Br J Ophthalmol 1999; 83: 290-294
    CrossrefPubMedSearch in Google Scholar
  • 6 Mardin CY, Horn FK, Jonas JB et al. Preperimetric glaucoma diagnosis by confocal scanning laser tomography of the optic disc. Br J Ophthalmol 1999; 83: 299-304
    CrossrefPubMedSearch in Google Scholar
  • 7 Burk ROW, Rohrschneider K, Takamoto T et al. Laser scanning tomography and stereophotogrammetry in three-dimensional optic disc analysis . Graefes Arch Clin Exp Ophthalmol 1993; 231: 193-198
    CrossrefPubMedSearch in Google Scholar
  • 8 Bartz-Schmidt KU, Weber J, Heimann K. Validity of two dimensional data obtained with the Heidelberg retina tomograph as verified by direct measurements in normal optic nerve heads. Ger J Ophthalmol 1994; 3: 400-405
    PubMedSearch in Google Scholar
  • 9 Burk R, Tuulonen A, Airaksinen PJ. Laser scanning tomography of localised nerve fibre layer defects. Brit J Ophthalmol 1998; 82: 1112-1117
    CrossrefPubMedSearch in Google Scholar
  • 10 Burk ROW, Rohrschneider K, Noack H et al. Volumetrische Analyse der Papille mittels Laser Scanning Tomographie. Parameterdefinition und Vergleich von Glaukom und Kontrollpapillen. Klin Monbl Augenheilkd 1991; 198: 522-529
    Thieme ConnectPubMedSearch in Google Scholar
  • 11 Hermann MM, Garway-Heath DF, Jonescu-Cuypers CP et al. Interobserver variability in confocal optic nerve analysis (HRT). Int Ophthalmol 2005; 26: 143-149
    PubMedSearch in Google Scholar
  • 12 Burk RO, Vihanninjoki K, Bartke T et al. Development of the standard reference plane for the Heidelberg retina tomograph. Graefes Arch Clin Exp Ophthalmol 2000; 238: 375-384
    CrossrefPubMedSearch in Google Scholar
  • 13 Mikelberg FS, Parfitt CM, Swindale NV et al. Ability of the Heidelberg Retina Tomograph to detect early glaucomatous visual field loss. J Glaucoma 1995; 4: 242-247
    PubMedSearch in Google Scholar
  • 14 Vihanninjoki K, Teesalu P, Burk RO et al. Search for an optimal combination of structural and functional parameters for the diagnosis of glaucoma. Multivariate analysis of confocal scanning laser tomography, blue-on-yellow visual field and retinal nerve fiber layer data. Graefes Arch Clin Exp Ophthalmol 2000; 238: 477-481
    CrossrefPubMedSearch in Google Scholar
  • 15 Burk ROW, Noack H, Rohrschneider K et al. Prediction of glaucomatous visual field defects by reference plane independent three-dimensional optic nerve head parameters. In: Wall M, Wild JM, (eds.) Perimetry update 1998/1999: Proceedings of the XIII International Perimetric Society Meeting. Walter Kugler, The Hague; 1999: 463-474
    Search in Google Scholar
  • 16 Bathija R, Zangwill L, Berry CC et al. Detection of early glaucomatous structural damage with confocal scanning laser tomography. J Glaucoma 1998; 7: 121-127
    PubMedSearch in Google Scholar
  • 17 Burk RO, König J, Rohrschneider K et al. 3-dimensionale Papillentopographie mittels Laser Scanning Tomographie: klinische Korrelation einer Clusteranalyse. Klin Monbl Augenheilkd 1994; 204: 504-512
    Thieme ConnectPubMedSearch in Google Scholar
  • 18 Rudnicka AR, Burk RO, Edgar DF et al. Magnification characteristics of fundus imaging systems. Ophthalmology 1998; 105: 2186-2192
    CrossrefPubMedSearch in Google Scholar
  • 19 Kruse FE, Burk RO, Völcker HE et al. Reproducibility of topographic measurements of the optic nerve head with laser tomographic scanning. Ophthalmology 1989; 96: 1320-1324
    PubMedSearch in Google Scholar
  • 20 Rohrschneider K, Burk RO, Völcker HE. Reproducibility of topographic data acquisition in normal and glaucomatous optic nerve heads with the laser tomographic scanner. Graefes Arch Clin Exp Ophthalmol 1993; 231: 457-464
    CrossrefPubMedSearch in Google Scholar
  • 21 Rohrschneider K, Burk RO, Kruse FE et al. Reproducibility of the optic nerve head topography with a new laser tomographic scanning device. Ophthalmology 1994; 101: 1044-1049
    PubMedSearch in Google Scholar
  • 22 Chauhan BC, LeBlanc RP, McCormick TA et al. Test-retest variability of topographic measurements with confocal scanning laser tomography in patients with glaucoma and control subjects. Am J Ophthalmol 1994; 118: 9-15
    Search in Google Scholar
  • 23 Brigatti L, Weitzman M, Caprioli J. Regional test-retest variability of confocal scanning laser tomography. Am J Ophthalmol 1995; 120: 433-440
    Search in Google Scholar
  • 24 Nicolela MT, Soares AS, Carrillo MM et al. Effect of Moderate Intraocular Pressure Changes on Topographic Measurements With Confocal Scanning Laser Tomography in Patients With Glaucoma. Arch Ophthalmol 2006; 124: 633-640
    CrossrefPubMedSearch in Google Scholar
  • 25 Wollstein G, Garway-Heath DF, Hitchings RA. Identification of early glaucoma cases with the scanning laser ophthalmoscope. Ophthalmology 1998; 105: 1557-1563
    CrossrefPubMedSearch in Google Scholar
  • 26 Swindale NV, Stjepanovic G et al. Automated analysis of normal and glaucomatous optic nerve head topography images. Invest Ophthalmol Vis Sci 2000; 41: 1730-1742
    PubMedSearch in Google Scholar
  • 27 Chauhan BC, Blanchard JW, Hamilton DC et al. Technique for detecting serial topographic changes in the optic disc and peripapillary retina using scanning laser tomography. Invest Ophthalmol Vis Sci 2000; 41: 775-782
    Search in Google Scholar
  • 28 Chauhan BC, McCormick TA, Nicolela MT et al. Optic disc and visual field changes in a prospective longitudinal study of patients with glaucoma: comparison of scanning laser tomography with conventional perimetry and optic disc photography. Arch Ophthalmol 2001; 119: 1492-1499
    Search in Google Scholar
  • 29 Zangwill LM, Weinreb RN, Beiser JA et al. Baseline topographic optic disc measurements are associated with the development of primary open-angle glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study. Arch Ophthalmol 2005; 123: 1188-1197
    CrossrefPubMedSearch in Google Scholar
  • 30 Parrish RK 2nd, Schiffman JC, Feuer WJ et al. Test-retest reproducibility of optic disk deterioration detected from stereophotographs by masked graders. Am J Ophthalmol 2005; 140: 762-764
    CrossrefPubMedSearch in Google Scholar
  • 31 Altangerel U, Bayer A, Henderer JD et al. Knowledge of chronology of optic disc stereophotographs influences the determination of glaucomatous change. Ophthalmology 2005; 112: 40-43
    CrossrefPubMedSearch in Google Scholar
  • 32 Jampel HD, Friedman D, Quigley H et al. Agreement among glaucoma specialists in assessing progressive disc changes from photographs in open-angle glaucoma patients. Am J Ophthalmol 2009; 147: 39-44
    CrossrefPubMedSearch in Google Scholar
  • 33 Kourkoutas D, Buys YM, Flanagan JG et al. Comparison of glaucoma progression evaluated with Heidelberg retina tomograph II versus optic nerve head stereophotographs. Can J Ophthalmol 2007; 42: 82-88
    PubMedSearch in Google Scholar
  • 34 O’Leary N, Crabb DP, Mansberger SL et al. Glaucomatous Progression in Series of Stereoscopic Photographs and Heidelberg Retina Tomograph Images. Arch Ophthalmol 2010; 128: 560-568
    CrossrefPubMedSearch in Google Scholar