PDF herunterladen
Synfacts 2013; 9(3): 0337
DOI: 10.1055/s-0032-1318224
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart · New York

Hydrogenolysis of Aryl or Benzyl Ethers Using Nickel Nanoparticles

Rezensent(en):
Yasuhiro Uozumi
,
Hiroaki Tsuji
Sergeev AG, Webb JD, Hartwig JF * University of California, Berkeley, USA
A Heterogeneous Nickel Catalyst for the Hydrogenolysis of Aryl Ethers without Arene Hydrogenation.

J. Am. Chem. Soc. 2012;
134: 20226-20229
CrossrefSuche in Google Scholar
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
15. Februar 2013 (online)

 
 als PDF herunterladen Lizenzen und Reprints

Key words

nickel nanoparticles - hydrogenolysis - aryl ethers - benzyl ethers

Significance

Nickel nanoparticles, generated in situ from Ni(CH2TMS)2(TMEDA) and t-BuONa, catalyzed the hydrogenolysis of aryl ethers 1 under H2 in m-xylene to give the corresponding products 2–5 (15 examples). The hydrogenolysis of benzyl ethers 6 also proceeded in the presence of the nickel nanoparticles under H2 atmosphere to afford the corresponding toluenes 7 and phenols 8 (4 examples).


#

Comment

The nickel nanoparticles were characterized by TEM, STEM, and EDS analyses. EDS analysis showed that the catalyst contained both nickel and sodium. From this result, the authors propose that t-BuONa stabilizes the nickel nanoparticles.


#
#


   Lizenzen und Reprints