Frustrated Lewis Pairs: An Elegant Concept for Catalysis

Abstract

The last decade has witnessed an intense increase in research in the area of frustrated Lewis pairs (FLP). This conceptually simple idea has demonstrated to be extremely fruitful from a synthetic point of view. In fact, FLP chemistry has been able to offer complementary approaches to transformations traditionally in the realm of metal catalysis. This Cluster contains a series of articles that present the most recent achievements in this field, including new concepts and applications.

Key words

frustrated Lewis pairs - catalysis - boranes - metal-free transformations - hydrogenation

• References


For reviews, see:
• 1a Stephan DW. Org. Biomol. Chem. 2008; 6: 1535
• 1b Stephan DW, Erker G. Angew. Chem. Int. Ed. 2010; 49: 46
• 1c Paradies J. Synlett 2013; 24: 777
• 2a Brown HC, Kanner B. J. Am. Chem. Soc. 1966; 88: 986
• 2b Roesler R, Piers WE, Parvez M. J. Organomet. Chem. 2003; 680: 218
• 2c Wittig G, Benz E. Chem. Ber. 1959; 92: 1999
• 2d Tochtermann W. Angew. Chem., Int. Ed. Engl. 1966; 5: 351
• 3 Welch GC, Juan RR. S, Masuda JD, Stephan DW. Science 2006; 314: 1124
• 4a Stephan DW. Dalton Trans. 2009; 3129
• 4b Rokob TA, Hamza A, Pápai I. J. Am. Chem. Soc. 2009; 131: 10701
• 5a Gier SJ, Stephan DW. J. Am. Chem. Soc. 2009; 131: 3476
• 5b Welch GC, Masuda JD, Stephan DW. Inorg. Chem. 2006; 45: 478
• 6 Dureen MA, Lough A, Gilbert TM, Stephan DW. Chem. Commun. 2008; 4303
• 7a Parks DJ, Piers WE. J. Am. Chem. Soc. 1996; 118: 9440
• 7b Parks DJ, Blackwell JM, Piers WE. J. Org. Chem. 2000; 65: 3090
• 7c Alcarazo M, Gomez C, Holle S, Goddard R. Angew. Chem. Int. Ed. 2010; 49: 5788
• 7d Chen D, Leich V, Pang F, Klankermayer J. Chem. Eur. J. 2012; 18: 5184
• 8 Dureen MA, Welch GC, Gilbert TM, Stephan DW. Inorg. Chem. 2009; 48: 9910
• 9a McCahill JS. J, Welch GC, Stephan DW. Angew. Chem. Int. Ed. 2007; 46: 4968
• 9b Ullrich M, Seto KS. H, Lough AJ, Stephan DW. Chem. Commun. 2009; 2335
• 9c Mömming CM, Kehr G, Wibbeling B, Fröhlich R, Schirmer B, Grimme S, Erker G. Angew. Chem. Int. Ed. 2010; 49: 2414
• 10a Chase PA, Welch GC, Jurca T, Stephan DW. Angew. Chem. Int. Ed. 2007; 46: 8050
• 10b Chase PA, Jurca T, Stephan DW. Chem. Commun. 2008; 1701
• 10c Jian CF, Blacque O, Berke H. Chem. Commun. 2009; 5518
• 10d Eros G, Mehdi H, Pápai I, Rokob TA, Király P, Tárkányi G, Soós T. Angew. Chem. Int. Ed. 2010; 49: 6559
• 11 Spies P, Schwendemann S, Lange S, Kehr G, Fröhlich R, Erker G. Angew. Chem. Int. Ed. 2008; 47: 7543
• 12 Segawa Y, Stephan DW. Chem. Commun. 2012; 48: 11963
• 13 Inés B, Palomas D, Holle S, Steinberg S, Nicasio JA, Alcarazo M. Angew. Chem. Int. Ed. 2012; 51: 12367
• 14a Greb L, Daniliuc CG, Bergander K, Paradies J. Angew. Chem. Int. Ed. 2013; 125: 5989
• 14b Nicasio JA, Steinberg S, Inés B, Alcarazo M. Chem. Eur. J. 2013; 19: 11016
• 15 Chen DJ, Wang YT, Klankermayer J. Angew. Chem. Int. Ed. 2010; 49: 9475