Organic Photoredox Catalysis as a General Strategy for Anti-Markovnikov Alkene Hydrofunctionalization

Abstract

The development of a general catalyst system for the ­direct anti-Markovnikov hydrofunctionalization of alkenes is pres­ented. A unique catalyst system comprised of an acridinium photooxidant and a hydrogen atom transfer reagent allows for a range of alkene anti-Markovnikov hydrofunctionalization reactions including hydroalkoxylation, hydroamination, and hydroacetoxylation.

Key words

hydroalkoxylation - hydroamination - alkenes - photo­redox - organocatalysis

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