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Synlett 2016; 27(11): 1725-1727
DOI: 10.1055/s-0035-1561851
DOI: 10.1055/s-0035-1561851
letter
Divergent Total Syntheses of Flavonoid Natural Products Isolated from Rosa rugosa and Citrus unshiu
Further Information
Publication History
Received 23 January 2016
Accepted after revision: 28 February 2016
Publication Date:
04 March 2016 (online)
Abstract
The concise and step-economical total syntheses of three hydroxyaurones and one polymethoxyflavone from readily available starting materials is described. A divergent synthetic strategy is employed, which centres on a common chalcone scaffold from which both the aurone and flavone frameworks can be accessed through the use of different oxidative cyclisation methods. These are the first reported total syntheses of these biologically interesting compounds.
Supporting Information
- Data accessibility: all data supporting this study are included in the paper and provided as Supporting Information accompanying this paper. It is available online at http://dx.doi.org/10.1055/s-0035-1561851.
- Supporting Information
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