A Practical ¹¹B NMR Evaluation of BH₃ Titer in Commercial Solutions

Abstract

Many reduction reactions require the use of BH₃, which is commercially available as complex in many different solvents. The determination of the content of BH₃ in such solutions could be an important issue when the stoichiometry of the reaction is concerned. A fast, direct, and reproducible method to establish the content of BH₃ in several solutions based on ¹¹B NMR analysis is reported.

Key words

borane - ¹¹B NMR - reductions - borane complexes

• References

• 1 Brown HC, Choi YM, Narasimhan S. J. Org. Chem. 1982; 47: 3153
• 2 Aldrich Technical Bulletin AL-218 . Sigma-Aldrich Co; Milwaukee: 2004
• 3 De Angelis S, De Renzo M, Degennaro L, Carlucci C, Luisi R. Org. Biomol. Chem. 2016; 14: 4304

For other reports from our group on the use of ¹¹B NMR, see:
• 4a Luisi R, Giovine A, Florio S. Chem. Eur. J. 2010; 9: 2683
• 4b Azzena U, Dettori G, Pisano L, Musio B, Luisi R. J. Org. Chem. 2011; 76: 2291
• 5a Kennedy JD. Boron . In Multinuclear NMR . Mason J. Plenum Press; NY: 1987. Chap. 8
• 5b Siedle AR. Ann. Rep. NMR Spectrosc. 1988; 20: 205
• 5c Hermanek S. Chem. Rev. 1992; 92: 325
• 6 Brown HC, Ravindran N. Inorg. Chem. 1977; 16: 2938
• 7 Young DE, McAchran GE, Shore SG. J. Am. Chem. Soc. 1966; 88: 4390
• 8a Wrackmeyer B. Ann. Rep. NMR Spectrosc. 1988; 20: 61
• 8b Phillips WD, Miller HC, Mutterties EL. J. Am. Chem. Soc. 1959; 81: 4496