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Synlett 2017; 28(16): 2135-2138
DOI: 10.1055/s-0036-1588874
DOI: 10.1055/s-0036-1588874
letter
Palladium-Catalyzed Regioselective Hydroarylation of Ynamides with Aryl Iodides: Easy Synthesis of Various Substituted Enamides Containing Stilbene Derivatives
Further Information
Publication History
Received: 20 April 2017
Accepted after revision: 19 May 2017
Publication Date:
06 July 2017 (online)
![](https://www.thieme-connect.de/media/synlett/201716/lookinside/thumbnails/st-2017-u0276-l_10-1055_s-0036-1588874-1.jpg)
Abstract
Palladium-catalyzed hydroarylation of ynamides has been developed. The desired coupling products were obtained in good yields and with high regioselectivities. Various aryl iodides can be used in this reaction, permitting the syntheses of many different kinds of enamides from ynamides.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588874.
- Supporting Information
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References and Notes
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For recent reviews on the chemistry of ynamines and ynamides, see:
For recent examples of transition-metal-catalyzed reactions of ynamide, see:
For recent reviews, see:
For reviews on the reactions of transition metals with alkynes, see: