Synthesis of Vismodegib via Directed C–H Chlorination

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Synfacts 2017; 13(11): 1113
DOI: 10.1055/s-0036-1591408

Synthesis of Natural Products and Potential Drugs

Contributor(s):

Philip Kocienski

Further Information

Publication Date:
19 October 2017 (online)

vismodegib - directed C–H chlorination - electrochemical chlorination - 5,7-dichloro-8-aminoquinoline - anodic oxidation - palladium catalysis