A New Enzyme Immunoassay for Soluble Fibrin in Plasma, with a High Discriminating Power for Thrombotic Disorders

R. Bos; G. H. Laterveer-Vreeswijk; D. Lockwood; K. Szewczyk; W. Nieuwenhuizen

doi:10.1055/s-0037-1614418

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1999; 81(01): 54-59
DOI: 10.1055/s-0037-1614418

Review Article

Schattauer GmbH

A New Enzyme Immunoassay for Soluble Fibrin in Plasma, with a High Discriminating Power for Thrombotic Disorders

R. Bos

¹ From TNO Prevention and Health, Gaubius Laboratory, Leiden, The Netherlands, Durham NC, USA

,

G. H. Laterveer-Vreeswijk

¹ From TNO Prevention and Health, Gaubius Laboratory, Leiden, The Netherlands, Durham NC, USA

,

D. Lockwood

²Organon Teknika Corporation, Durham NC, USA

,

K. Szewczyk

²Organon Teknika Corporation, Durham NC, USA

,

W. Nieuwenhuizen

¹ From TNO Prevention and Health, Gaubius Laboratory, Leiden, The Netherlands, Durham NC, USA

› Author Affiliations

References
1 Doolittle RF. Fibrinogen and fibrin. Sci Am 1981; 245: 92-101.
2 Sasaki T, Page IH, Shainoff JR. Soluble complexes of fibrinogen and fibrin. Science 1966; 152: 1069-71.
3 Alkajersig N, Fletcher AP. Formation of soluble fibrin oligomers in purifed system and in plasma. Biochem J 1983; 213: 75-83.
4 Wieding JU, Hosius C. Determination of soluble fibrin: a comparison of four methods. Thromb Res 1992; 65: 745-56.
5 Müller-Berghaus G, Hasegawa H. Pathophysiology of generalized coagulation. Sem Thromb Hemost 1977; 3: 209-46.
6 Bowie EJ, Owen CA. The clinical pathology of intravascular coagulation. Bibl Haematol 1983; 49: 217-44.
7 Kisker CT, Rush R. Detection of intravascular coagulation. J Clin Invest 1971; 50: 2235-41.
8 Vogel G, Spanuth E. Predictive value of fibrin monomers in postoperative deep vein thrombosis. Klin Wochenschr 1990; 68: 1020-6.
9 Francis CW, Conaghan DG, Scott WL, Marder VJ. Increased plasma concentrations of cro-linked fibrin polymers in acute myocardial infarction. Circulation 1987; 75: 1170-6.
10 Okajima K, Koga S, Okabe H, Inoue M, Takatsuki K. Characterisation of the fibrinolytic state by measuring stable cro-linked fibrin degradation products in disseminated intravascular coagulation associated with acute promyelocytic leukemia. Acta Haematol 1989; 81: 15-8.
11 Nieuwenhuizen W. Soluble fibrin as a marker for a pre-thrombotic state: a mini-review. Blood Coag Fibrinol 1993; 4: 93-6.
12 Ginsberg JS, Siragusa S, Douketis J, Johnston M, Moffat K, Stevens P, Brill-Edwards P, Panju A, Patel M. Evaluation of a soluble fibrin assay in patients with suspected deep venous thrombosis. Thromb Haemost 1995; 74: 833-6.
13 Ginsberg JS, Siragusa S, Douketis J, Johnston M, Moffat K, Donovan D, McGinnis J, Brill-Edwards P, Panju A, Patel M, Weitz JI. Evaluation of a soluble fibrin assay in patients with suspected pulmonary embolism. Thromb Haemost 1996; 75: 551-4.
14 Wieding JU, Eisinger G, Köstering H. Determination of soluble fibrin by turbidimetry of its protamin sulphate-induced paracoagulation. J Clin Chem Clin Biochem 1989; 27: 57-63.
15 Wiman B, Rånby M. Determination of soluble fibrin in plasma by a rapid and quantitative spectrophotometric assay. Thromb Haemost 1986; 55: 189-93.
16 Dempfle C-E, Pfitzner SA, Dollman M, Huck K, Stehle G, Heene DL. Comparison of immunological and functional assays for measurement of soluble fibrin. Thromb Haemost 1995; 74: 673-9.
17 Lill H, Spannagl M, Trauner A, Schramm W, Shuller D, Ofenloch-Haehnle B, Draeger B, Naser W, Dessauer A. A new immunoassay for soluble fibrin enables a more sensitive detection of the activation state of blood coagulation in vivo. Blood Coag Fibrinol 1993; 4: 97-102.
18 Vogel G, Dempfle C-E, Spannagl M, Leskopf W. The value of quantitative fibrin monomer determination in the early diagnosis of post operative deep vein thrombosis. Thromb Res 1996; 81: 241-51.
19 Carville DGM, Dimitreievic N, Walsh M, Digirolamo T, Brill EM, Drew N, Gargan PE. Thrombus precursor protein (TpP): marker of thrombosis early in the pathogenesis of myocardial infarction. Clin Chem 1996; 42: 1537-41.
20 Nieuwenhuizen W, Hoegee-de Nobel E, Laterveer R. A rapid monoclonal antibody-based enzyme immunoassay (EIA) for the quantitative determination of soluble fibrin in plasma. Thromb Haemost 1992; 68: 273-7.
21 Lee LV, Ewald GA, McKenzy CR, Eisenberg PR. The relationship of soluble fibrin and cro-linked fibrin degradation products to the clinical course of myocardial infarction. Arterioscl Thromb Vasc Biol 1997; 17: 628-33.
22 Schielen WJG., Adams HPHM, Van Leuven K, Voskuilen M, Tesser GI, Nieuwenhuizen W. The sequence γ-(312-324) is a fibrin specific epitope. Blood 1991; 77: 2169-73.
23 Hoegee-de Nobel E, Voskuilen M, Briët E, Brommer EJP, Nieuwenhuizen W. A monoclonal antibody-based quantitative enzyme immunoassay for the determination of plasma fibrinogen concentrations. Thromb Haemost 1988; 60: 415-8.
24 Bos ES, Van der Doelen AA, Van Rooij N, Schuurs AHWM. 3,3’,5,5’-tetramethyl benzidine as an Ames test negative chromogen for horse-radish peroxidase in enzyme immunoassay. J Immunoassay 1981; 60: 187-204.
25 Koppert PW, Kuipers W, Hoegee-de Nobel E, Brommer EJP, Koopman J, Nieuwenhuizen W. A quantitative enzyme immunoassay for primary fibrinogenolysis products in plasma. Thromb Haemost 1987; 57: 25-8.
26 Koopman J, Haverkate F, Koppert PW, Nieuwenhuizen W, Brommer EJP, Van der Werf WGC. New enzyme immunoassay of fibrin-fibrinogen degradation products in plasma using a monoclonal antibody. J Lab Clin Med 1987; 109: 75-84.
27 Bos R, Van Leuven CJM, Stolk J, Hiemstra PS, Ronday HK, Nieuwenhuizen W. An enzyme immunoassay for polymorphonuclear leucocyte-mediated fibrinogenolysis. Eur J Clin Inv 1997; 27: 148-56.
28 Pfitzner SA, Dempfle C-E, Matsuda M, Heene DL. Fibrin detected in plasma of patients with disseminated intravascular coagulation by fibrin-specific antibodies constists primarily of high molecular weight FXIIIa-crosslinked and plasmin-modified complexes partially containing fibrinopeptide A. Thromb Haemost 1997; 78: 1069-78.
29 Emeis JJ, Verheijen JH, Ronday HK, De Maat MPM, Brakman P. Progress in clinical fibrinolysis. Fibrinolysis & Proteolysis 1997; 11: 67-84.
30 Nieuwenhuizen W. A reference material for harmonisation of D-Dimer assays. Thromb Haemost 1997; 77: 1031-3.