Topography-Guided PRK and Crosslinking in Eyes with Keratoconus and Post-LASIK Ectasia

Abstract

Topography-guided photorefractive keratectomy (TG-PRK) combined with corneal collagen crosslinking (CXL) has been shown to potentially improve vision and stabilize progression in patients with keratoconus (KC). We attempted to reproduce the previously published results using a different laser platform (AMARIS 500E) in patients with KC and post-LASIK ectasia (PLE). All of the 9 included eyes showed improved topography (Kmax, Kmean, RMS HOA, vertical coma, cylinder; p < 0.05) and improved visual acuity (BCVA, UCVA; p < 0.05) after 18 months. Despite some still uncontrollable factors, the combination of TG-PRK and CXL may be a promising option to regularize and stabilize corneas with KC and PLE and improve visual acuity.

Zusammenfassung

Es wurde gezeigt, dass topografiegesteuerte Keratektomie (TG-PRK) in Kombination mit kornealem Crosslinking (CXL) bei Patienten mit Keratokonus (KK) potenziell den Visus verbessern und eine Progression aufhalten kann. Wir versuchten, die publizierten Resultate auf einer anderen Laserplattform (AMARIS 500E) zu reproduzieren. Alle 9 eingeschlossenen Augen zeigten nach 18 Monaten eine verbesserte Topografie (Kmax, Kmean, RMS HOA, vertical coma, Zylinder; p < 0.05) und einen verbesserten Visus (BCVA, UCVA; p < 0.05). Trotz einigen noch unkontrollierbaren Faktoren könnte die Kombination von TG-PRK und CXL eine vielversprechende Option zur Stabilisierung und Regularisierung von Hornhäuten mit KK und PLE sein und den Visus verbessern.

Key words

topography-guided photorefractive keratotomy - PRK - uv crosslinking - CXL - keratoconus - post-LASIK ectasia

Schlüsselwörter

topografiegesteuerte photorefraktive Keratektomie - PRK - korneales Crosslinking - CXL - Keratokonus - post-LASIK-Ektasie

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