Maiti S,
Ghosh P,
Raja D,
Ghosh S,
Chatterjee S,
Sankar V,
Roy S,
Lahiri GK,
Maiti D.
*
Indian Institute of Technology Bombay, Mumbai, India
Light-Induced Pd Catalyst Enables C(
sp
2)–C(
sp
2) Cross-Electrophile Coupling Bypassing the Demand for Transmetalation.
Nat. Catal. 2024;
7: 285-294
DOI:
10.1038/s41929-024-01109-4
Key words
palladium catalysis - photocatalysis - cross-electrophile coupling - biaryl coupling
Significance
Maiti and co-workers report a highly chemoselective cross-coupling of (hetero)aryl halides under palladium visible-light catalysis. Key to success was ligand design enabling differing modes of oxidative addition between the (pseudo)halides.
Comment
Support for the proposed hybrid aryl Pd(I)-radical species was achieved by trapping the corresponding species with N-methyl pyrrole and DMPO. The corresponding DMPO adduct was subsequently characterized by EPR.
