HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors That Prematurely Activate Protease Causing Cell Death

Antonia F. Stepan; Nicholas A. Meanwell

doi:10.1055/s-0043-1773094

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Synfacts 2024; 20(03): 0308
DOI: 10.1055/s-0043-1773094

Innovative Drug Discovery and Development

HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors That Prematurely Activate Protease Causing Cell Death

Contributor(s):

Antonia F. Stepan (Roche)

,

Nicholas A. Meanwell (Baruch S. Blumberg Institute U. Michigan)

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Key words

HIV-1 infection - HIV-1 cure research - cryptic HIV-1 protease activation - non-nucleoside reverse transcriptase inhibitor - compound-induced cell killing

Publication History

Article published online:
14 February 2024

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany