Iridium-HetPHOX Complexes for the Catalytic Asymmetric Hydrogenation of Olefins and Imines

Abstract

Heterocyclic phosphino oxazolines derived from thiophene and benzo[b]thiophene (HetPHOX) form highly active iridium complexes for the enantioselective hydrogenation of olefins and imines.

Key words

hydrogenation - asymmetric catalysis - ligands - iridium - alkenes

References

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8

Single crystals of complex 6c were obtained by layering a chloroform solution with pentane. Crystallographic data have been deposited under CCDC 203958.

9

Smidt, S. P.; Mukherjee, P.; Pfaltz, A.; Neuburger, M., unpublished results.