Synlett 2004(1): 81-84  
DOI: 10.1055/s-2003-43358
LETTER
© Georg Thieme Verlag Stuttgart · New York

Preparation and Reactions of Polyfunctional Magnesium Arylcuprates Obtained by an Iodine-Copper Exchange

Xiaoyin Yang, Paul Knochel*
Department of Chemistry, Ludwig-Maximilians-Universität München, Butenandtstrasse 5-13, Haus F, 81377 München, Germany
Fax: +49(89)218077680; e-Mail: knoch@cup.uni-muenchen.de;
Further Information

Publication History

Received 6 October 2003
Publication Date:
26 November 2003 (online)

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Abstract

The preparation of polyfunctional magnesium cuprates of type 1 can be achieved via an iodine-copper exchange reaction using the cyclic magnesium cuprate 3. A range of functional groups like an ester, halide (F, Br), nitrile or even a ketone can be tolerated. The new cuprates can be acylated and allylated in good yields leading to a range of polyfunctional products.