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Am J Perinatol 2003; 20(7): 347-352
DOI: 10.1055/s-2003-45288
Copyright © 2003 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Severe Neutrophilia in an Infant with Persistent Pulmonary Hypertension of the Newborn

Cyril Engmann, Steven M. Donn
  • Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of Michigan Health System, Ann Arbor, Michigan
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Publication History

Publication Date:
04 December 2003 (online)

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ABSTRACT

We report the case of a term male infant with severe persistent pulmonary hypertension of the newborn, who developed massive neutrophilia of unknown etiology. An extensive evaluation failed to disclose an obvious cause for his neutrophilia. A bone marrow aspirate was performed and was consistent with a leukemoid reaction. This paper reviews the neonatal leukemoid reaction and its significance.

KEYWORDS

Newborn - leukemoid reaction - persistent pulmonary hypertension - neutrophilia

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