Synthesis of 2-Substituted Cyclobutanones as γ-Irradiation Marker Products of Lipid-Containing Foods

Abstract

A short and efficient synthesis is described towards 2-dodecyl-, 2-tetradecyl, 2-(5-tetradecenyl)- and 2-(5,8-tetradeca­dienyl)cyclobutanones, which are specific markers of gamma-irradiated foodstuffs, e.g. chicken meat and liquid whole egg.

Key words

cyclobutanones - total synthesis - alkynes - alkenes - alkylation

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12

Colpaert, J.; Kesteleyn, B.; Boterberg, S.; Stevens, C.; De Kimpe, N. New Method for the Synthesis of (Z)-2-(5-Tetradecenyl)cyclobutanone as Marker for Irradiated Foodstuffs, 4^th International Conference on Agro and Food Physics, May 16-20, 2000, Instanbul (Turkey), Abstract 11, 74.