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DOI: 10.1055/s-2005-858099
© Georg Thieme Verlag KG Stuttgart · New York
„White bowel - die weiße Darmwand”. Sonographischer Ausdruck einer mesenterialen Lymphstauung?
“White Bowel”. A Sonographic Sign of Intestinal Lymph Edema?Publication History
eingereicht: 21.7.2004
angenommen: 12.1.2005
Publication Date:
25 April 2005 (online)
Zusammenfassung
Ziel: Der Begriff „white bowel” wurde erstmals von uns bei einem Patienten mit HIV-assoziierter Enteropathie und Mycobacterium avium-intracellulare-Infektion geprägt. Ziel der Arbeit war die genaue Beschreibung der echoreichen Darmwandveränderungen und die Darstellung möglicher Ursachen. Material und Methoden: Insgesamt wurden die Daten von zehn Patienten ausgewertet, bei denen wir dieses Phänomen beobachtet haben und die in Bilddatensammlungen erfasst waren. Besonderes Augenmerk wurde auf die Echogenität der einzelnen Darmwandschichten und auf Veränderungen im Mesenterium wie Lymphknotenvergrößerungen und Venenthrombosen gelegt. Ergebnisse: Bei den erfassten zehn Fällen handelte es sich um Patienten mit Mycobacterium avium-intracellulare-Infektionen (n = 3), einheimischer Sprue und T-Zell-Lymphom (n = 2), Karzinomen des Dünn- und Dickdarms (n = 3) und Morbus Whipple (n = 2). Typisch war eine echoreich verdickte Dünndarmwand, vor allem die Mukosa und teilweise auch die Submukosa betreffend. Begleitend war fast immer eine deutliche echoarme oder seltener auch echoreiche mesenteriale Lymphadenopathie zu beobachten. In drei Fällen lag auch eine Mesenterialvenenthrombose vor. Schlussfolgerung: Das Phänomen der weißen Darmwand trat bei verschiedenen Erkrankungen auf, wobei in der Mehrzahl auch eine deutliche mesenterielle Lymphadenopathie vorhanden war. Dies lässt einen Zusammenhang mit einem Lymphaufstau des Darms vermuten.
Abstract
Aim: We recently introduced the term “white bowel” to describe the hyperechoic appearance of the bowel wall found in a patient with HIV-associated enteropathy. The aim of this study was to describe changes of the bowel wall and to demonstrate possible causes of this phenomenon. Patients and Methods: 10 patients identified as showing this phenomenon were enrolled in this study. The ultrasound examinations of the patients were re-evaluated with special regard to the echogenicity of the different layers of the bowel wall, to mesenteric lymph nodes, and to thrombosis of the mesenteric vein. Results: Diagnosis in these 10 patients included: HIV-associated enteropathy aggravated by Mycobacterium avium-intracellulare infection (n = 3); endemic coeliac disease and complications arising from T-cell lymphoma (n = 2); carcinoma of the small and large intestine (n = 3); Whipple’s disease (n = 2). Sonography typically showed echogenic thickening of the wall of the small intestine - mainly of the mucosal layer. Enlarged mesenteric lymph nodes (with both hypoechoic and occasionally hyperechoic appearance) were present in the majority of cases. In 3 cases, mesenteric vein thrombosis was also demonstrable. Conclusion: The “white bowel” was found in patients with different diseases. Most of the patients showed enlargement of the mesenteric lymph nodes. Lymph oedema of the bowel wall probably constitutes the main reason for this phenomenon.
Schlüsselwörter
Sonographie - Lymphödem - Darmerkrankungen - M. Whipple - Mycobacterium avium-intracellulare-Infektion
Key words
Ultrasonography - lymph oedema - intestinal diseases - Whipple disease - mmycobacterium avium-intracellulare infection
Literatur
- 1 Puylaert J B, Rutgers P H, Lalisang R I. et al . A prospective study of ultrasonography in the diagnosis of appendicitis. N Engl J Med. 1987; 317 666-669
- 2 Beyer D, Rieker O R, Kaiser C. et al . Sonography in suspected appendicitis: a decisive factor in diagnosis and therapy? Results of a prospective study of 669 patients. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1990; 152 510-515
- 3 Uebel P, Weiss H, Trimborn C P. et al . Ultrasound diagnosis of acute appendicitis: possibilities and limits of the method: results of prospective and retrospective clinical studies. Ultraschall in Med. 1996; 17 100-105
- 4 Schwerk W B, Wichtrup B, Maroske D. et al . Ultrasonics in acute appendicitis: a prospective study. Dtsch Med Wochenschr. 1988; 113 493-499
- 5 Rettenbacher T, Hollerweger A, Gritzmann N. et al . Appendicitis: should diagnostic imaging be performed if the clinical presentation is highly suggestive of the disease?. Gastroenterology. 2002; 123 992-998
- 6 Rettenbacher T, Hollerweger A, Macheiner P. et al . Outer diameter of the vermiform appendix as a sign of acute appendicitis: evaluation at US. Radiology. 2001; 218 757-762
- 7 Yacoe M E, Jeffrey R B Jr. Sonography of appendicitis and diverticulitis. Radiol Clin North Am. 1994; 32 899-912
- 8 Verbanck J, Lambrecht S, Rudgeerts L. et al . Can sonography diagnose acute colonic diverticulitis in patients with acute intestinal inflammation? A prospective study. J Clin Ultrasound. 1989; 17 661-666
- 9 Schwerk W B, Schwarz S, Rothmund M. Sonography in acute colonic diverticulitis. Dis Colon Rectum. 1992; 35 1077-1084
- 10 Wilson S R, Toi A. The value of sonography in the diagnosis of acute diverticulitis of the colon. AJR. 1990; 154 1199-1202
- 11 Hollerweger A, Macheiner P, Gritzmann N. Acute left lower quadrant abdominal pain: ultrasonographic differential diagnosis. Ultraschall in Med. 2003; 24 7-16
- 12 Hollerweger A, Macheiner P, Rettenbacher T. et al . Colonic diverticulitis: diagnostic value and appearance of inflamed diverticula-sonographic evaluation. Eur Radiol. 2001; 11 1956-1963
- 13 Seitz K, Merz M. Ultrasound detection of bowel obstruction. Ultraschall in Med. 1998; 19 242-249
- 14 Schmutz G R, Benko A, Fournier L. et al . Small bowel obstruction: role and contribution of sonography. Eur Radiol. 1997; 7 1054-1058
- 15 Ko Y T, Lim J H, Lee D H. et al . Small bowel obstruction: sonographic evaluation. Radiology. 1993; 188 649-653
- 16 Meckler U, Caspary W F, Clement T. et al . Sonography in Crohn’s disease. Z Gastroenterol. 1991; 29 355-359
- 17 Valette P J, Rioux M, Pilleul F. et al . Ultrasonography in chronic inflammatory bowel diseases. Eur Radiol. 2001; 11 1859-1866
- 18 Puylaert J B. Mesenteric adenitis and acute terminal ileitis: US evaluation using graded compression. Radiology. 1986; 161 691-695
- 19 Puylaert J B. Ultrasound of acute GI tract conditions. Eur Radiol. 2001; 11 1867-1877
- 20 Gritzmann N, Hollerweger A, Macheiner P. et al . Transabdominal sonography of the gastrointestinal tract. Eur Radiol. 2002; 12 1748-1761
- 21 Dietrich C F, Brunner V, Lembcke B. Intestinal ultrasound in rare small and large intestinal diseases. Z Gastroenterol. 1998; 36 955-970
- 22 Truong M, Atri M, Bret P M. et al . Sonographic appearance of benign and malignant conditions of the colon. AJR. 1998; 170 1451-1455
- 23 Bolondi L, Ferrentino M, Trevisani F. et al . Sonographic appearance of pseudomembranous colitis. J Ultrasound Med. 1985; 4 489-492
- 24 Downey D B, Wilson S R. Pseudomembranous colitis: sonographic features. Radiology. 1991; 180 61-64
- 25 Glass-Royal M C, Choyke P L, Gootenberg J E. et al . Sonography in the diagnosis of neutropenic colitis. J Ultrasound Med. 1987; 6 671-673
- 26 Dirks K, Deuerling J, Lutz H. Sonography in hereditary angioedema: typical findings demonstrated by the example of 3 cases. Ultraschall Med. 2001; 22 186-190
- 27 Klein S A, Martin H, Schreiber-Dietrich D. et al . A new approach to evaluating intestinal acute graft-versus-host disease by transabdominal sonography and colour Doppler imaging. Br J Haematol. 2001; 115 929-934
- 28 Dietrich C F, Brunner V, Seifert H. et al . Intestinal B-mode sonography in patients with endemic sprue: intestinal sonography in endemic sprue. Ultraschall in Med. 1999; 20 242-247
- 29 Hirche T O, Russler J, Schroder O. et al . The value of routinely performed ultrasonography in patients with Crohn disease. Scand J Gastroenterol. 2002; 37 1178-1183
- 30 Dietrich C F, Zeuzem S, Caspary W F. et al . Ultrasound lymph node imaging in the abdomen and retroperitoneum of healthy probands. Ultraschall in Med. 1998; 19 265-269
- 31 Rettenbacher T, Hollerweger A, Macheiner P. et al . Adult celiac disease: US signs. Radiology. 1999; 211 389-394
- 32 Dietrich C F, Ignee A, Seitz K H. et al . Duplex sonography of visceral arteries. Ultraschall in Med. 2001; 22 247-257
- 33 Frisoli J K, Desser T S, Jeffrey R B. Thickened submucosal layer: a sonographic sign of acute gastrointestinal abnormality representing submucosal edema or hemorrhage. AJR. 2000; 175 1595-1599
- 34 Herbay A von. Whipple’s disease: histologic diagnosis after the discovery of Tropheryma whippelii. Pathologe. 2001; 22 82-88
- 35 Horton K M, Fishman E K. Uncommon inflammatory diseases of the small bowel: CT findings. AJR Am J Roentgenol. 1998; 170 385-388
- 36 Khairy P, Graham A F. Whipple’s disease and the heart. Can J Cardiol. 1996; 12 831-834
- 37 Herbay A von, Windler F, Heckmayr M. et al . Abdominal pseudotumor as the clinical manifestation of Whipple’s disease: T-cell index as an indicator of disease activity and a parameter of the duration of therapy?. Dtsch Med Wochenschr. 1987; 112 1621-1625
- 38 Herbay A von, Otto H F. Whipple’s disease: a report of 22 patients. Klin Wochenschr. 1988; 66 533-539
- 39 Albano O, Carrieri V, Vinciguerra V. et al . Ultrasonic findings in Whipple’s disease. J Clin Ultrasound. 1984; 12 286-288
- 40 Bruggemann A, Burchardt H, Lepsien G. Sonographical findings in Whipple’s disease: a case report with regard to the literature. Surg Endosc. 1992; 6 138-140
- 41 Graham P M, Kelly C R, Booth J A. Ultrasonic appearance of abdominal lymph nodes in a case of Whipple’s disease. J Clin Ultrasound. 1983; 11 388-390
OA Dr. Alois Hollerweger
Abteilung für Radiologie und Nuklearmedizin, KH Barmherzige Brüder
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